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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FGFR1 All Species: 35.15
Human Site: T521 Identified Species: 70.3
UniProt: P11362 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P11362 NP_056934.2 822 91868 T521 K M L K S D A T E K D L S D L
Chimpanzee Pan troglodytes XP_001171131 821 91764 T520 K M L K S D A T E K D L S D L
Rhesus Macaque Macaca mulatta XP_001090823 731 81824 A473 L Y V I V E Y A S K G N L R E
Dog Lupus familis XP_848780 820 91633 T519 K M L K S D A T E K D L S D L
Cat Felis silvestris
Mouse Mus musculus P16092 822 91962 T521 K M L K S D A T E K D L S D L
Rat Rattus norvegicus Q04589 822 91806 T521 K M L K S D A T E K D L S D L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P21804 819 91558 T519 K M L K S D A T E K D L S D L
Frog Xenopus laevis P22182 812 90484 S515 K M L K S D A S E K D L S D L
Zebra Danio Brachydanio rerio Q90Z00 810 91023 T508 K M L K S D A T E K D L S D L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q09147 1052 117795 T755 K M V K E E H T D T D M A S L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q10656 1040 118938 H679 K K L K M S A H E K E L I D L
Sea Urchin Strong. purpuratus Q26614 972 110463 M680 K M L K A N A M D R E F S D L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 85.5 98.9 N.A. 98.4 97.6 N.A. N.A. 91.4 78.2 72.1 N.A. 30.6 N.A. 30.6 35.6
Protein Similarity: 100 99.7 86.7 99.3 N.A. 99.1 98.6 N.A. N.A. 96.1 89.7 83.6 N.A. 45.4 N.A. 47.1 53
P-Site Identity: 100 100 6.6 100 N.A. 100 100 N.A. N.A. 100 93.3 100 N.A. 40 N.A. 60 53.3
P-Site Similarity: 100 100 20 100 N.A. 100 100 N.A. N.A. 100 100 100 N.A. 73.3 N.A. 66.6 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 9 0 84 9 0 0 0 0 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 67 0 0 17 0 75 0 0 84 0 % D
% Glu: 0 0 0 0 9 17 0 0 75 0 17 0 0 0 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % G
% His: 0 0 0 0 0 0 9 9 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 9 0 0 0 0 0 0 0 0 9 0 0 % I
% Lys: 92 9 0 92 0 0 0 0 0 84 0 0 0 0 0 % K
% Leu: 9 0 84 0 0 0 0 0 0 0 0 75 9 0 92 % L
% Met: 0 84 0 0 9 0 0 9 0 0 0 9 0 0 0 % M
% Asn: 0 0 0 0 0 9 0 0 0 0 0 9 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 9 0 0 0 9 0 % R
% Ser: 0 0 0 0 67 9 0 9 9 0 0 0 75 9 0 % S
% Thr: 0 0 0 0 0 0 0 67 0 9 0 0 0 0 0 % T
% Val: 0 0 17 0 9 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 0 0 0 9 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _